Restylane Refyne
Soften laugh lines and smile lines naturally, with a filler designed to move with your face — not against it.

Before and after gallery
Real results from honest, board-certified dermatology in South Florida
Lines That Show Up When You Smile Shouldn't Bother You When You're Not
If you've noticed deeper lines forming around your mouth and nose, you're not alone. Nasolabial folds and marionette lines are some of the most common cosmetic concerns we see at Dermatology Experts, and they tend to become more pronounced in South Florida's sun-rich environment, where years of UV exposure can accelerate the breakdown of collagen and elastin in the skin.
The frustrating part for many patients is that these lines don't reflect how they feel on the inside. You want a refreshed look, but you also want to still look like yourself. That balance is exactly what Restylane Refyne is designed to achieve.
What Is Restylane Refyne?
Restylane Refyne is an FDA-approved hyaluronic acid dermal filler specifically formulated to smooth moderate to severe facial lines while preserving your natural facial movement. Unlike older fillers that could leave skin looking stiff or overdone, Refyne uses XpresHAn Technology to create a soft, flexible gel that adapts as your face moves.
- Active ingredient: Hyaluronic acid, a substance naturally produced by your body
- Primary targets: Nasolabial folds (laugh lines) and marionette lines
- FDA-approved for the correction of moderate to severe facial wrinkles and folds
- XpresHAn Technology: Cross-links the hyaluronic acid in a way that allows the gel to flex with your expressions
- Results typically last up to 12 months, though individual results vary
- Contains lidocaine to help minimize discomfort during injection
- No animal-derived ingredients
The goal of Restylane Refyne is subtle correction, not transformation. Patients often describe looking like a more rested, refreshed version of themselves rather than someone who has had obvious cosmetic work done.
What to Expect at Your Appointment
Getting Restylane Refyne at Dermatology Experts is a straightforward in-office treatment. Here is what a typical appointment looks like from start to finish.
- Consultation: Your provider will assess the depth and placement of your lines and discuss your goals. This is a good time to ask questions and set realistic expectations
- Preparation: The treatment area is cleansed and a topical numbing cream may be applied to improve comfort
- Injection: Refyne is carefully injected in small amounts along the treatment area using a fine needle. The filler contains lidocaine, which further reduces any stinging sensation
- Session length: Most appointments take between 30 and 60 minutes, including consultation time
- Downtime: Most patients return to their normal activities the same day. Mild swelling, redness, or bruising at the injection site is common and typically resolves within a few days
- Post-treatment: Avoid intense exercise, sun exposure, and alcohol for 24 to 48 hours after treatment. Do not massage or apply pressure to the treated area
Because Refyne contains lidocaine, most patients find the experience more comfortable than they expected going in.
Results: What You Can Realistically Expect
Most patients begin to see results immediately after treatment, with continued improvement as any swelling resolves over the first one to two weeks. The final result typically settles in within two weeks of your appointment.
- Smoother, softer appearance along the nasolabial folds and marionette lines
- Natural-looking results that move with your facial expressions
- Results may last up to 12 months, though this varies by patient, metabolism, and lifestyle factors
- South Florida's active outdoor lifestyle can influence how long results last. Sun protection and good skincare habits can help maintain your outcome
- Many patients choose to return for a touch-up treatment before results fully fade to maintain consistency
Restylane Refyne is not a permanent solution, but many patients find that consistent treatments over time can help maintain a more youthful baseline as the skin responds to ongoing hyaluronic acid support.
Who Is a Good Candidate for Restylane Refyne?
Restylane Refyne may be a good fit if you relate to any of the following.
- You have moderate to severe laugh lines or marionette lines that bother you at rest
- You want to look refreshed without looking like you've had work done
- You're concerned about fillers that look stiff or unnatural when you smile or talk
- You are in good overall health with no active skin infections near the treatment area
- You are not pregnant or breastfeeding
- You have realistic expectations about what filler can and cannot do
- You've tried skincare and are ready for a more noticeable, longer-lasting correction
Restylane Refyne may not be appropriate for patients with certain bleeding disorders, a history of severe allergic reactions, or active inflammation near the planned injection site. Your provider will review your full health history before proceeding.
Frequently Asked Questions About Restylane Refyne
How is Restylane Refyne different from other Restylane products?
The Restylane family includes several fillers, each formulated for a different purpose. Refyne is specifically designed for moderate to severe lines that form around the nose and mouth, using XpresHAn Technology to allow for flexible, natural-looking movement. Other products in the line, like Restylane Lyft or Restylane Silk, are optimized for different areas and treatment goals. Your provider can help you determine which product, or combination of products, best fits your concerns.
Does Restylane Refyne hurt?
Most patients describe the sensation as mild to moderate pressure or a slight sting during injection. Restylane Refyne contains lidocaine, a local anesthetic built directly into the formula, which helps reduce discomfort as the treatment progresses. A topical numbing cream applied before your session can further improve comfort. The majority of patients find the experience very manageable.
How long does Restylane Refyne last?
Clinical studies have shown that results from Restylane Refyne can last up to 12 months for many patients, though individual results vary based on metabolism, the area treated, and lifestyle factors. Patients who spend significant time outdoors in South Florida's sun may notice that results fade somewhat faster without consistent sun protection. Many patients return for a maintenance treatment before their results fully resolve to stay ahead of the lines returning.
Is there any downtime after Restylane Refyne?
Restylane Refyne is considered a lunchtime treatment for most patients, meaning you can return to work and daily activities the same day. You may notice mild swelling, redness, or light bruising at the injection sites, which generally clears within a few days. We recommend avoiding strenuous exercise, alcohol, and prolonged sun exposure for 24 to 48 hours after your appointment. Arnica supplements or cold compresses can help minimize any bruising, and your provider will give you specific aftercare guidance.
Is Restylane Refyne covered by insurance?
Restylane Refyne is an elective cosmetic treatment and is not covered by health insurance. However, many patients use their HSA or FSA funds to cover the cost, so it is worth checking with your plan administrator. Our team is happy to discuss pricing during your consultation so you have a clear picture of the investment before your appointment. Same-day appointments are available if you're ready to move forward.
Why Choose Dermatology Experts for Restylane Refyne in South Florida
There is a meaningful difference between receiving filler at a medspa and receiving it at a dermatology practice led by a board-certified physician. At Dermatology Experts, your care is guided by Dr. Angelo Ayar, MD, FAAD, who completed his dermatology residency at the University of Michigan, one of the most respected training programs in the country, and holds a research background in skin cancer and skin health.
When you come in for Restylane Refyne, you are not just getting an injection. You are getting a full facial assessment from a provider who understands skin at a cellular level, who can identify when a cosmetic concern has a medical component that warrants attention, and who brings the same clinical precision to a filler appointment as to a surgical procedure.
- Three convenient locations across South Florida: Miami, Parkland, and Tamarac
- Serving patients throughout Broward County, Miami-Dade County, Coral Springs, Fort Lauderdale, Pompano Beach, and Boca Raton
- Medical, surgical, and cosmetic dermatology under one roof, so your full skin health is always in view
- Over 500 five-star reviews from patients who consistently describe feeling cared for, heard, and at ease
- Same-day appointments available for patients ready to schedule
- A team known for warmth and attentiveness at every step of the visit
Patients drive from across South Florida to see Dr. Ayar and his team because the experience feels different here. You feel like a person, not an appointment slot.
Schedule Your Restylane Refyne Consultation in South Florida
If you're ready to soften those lines around your mouth and nose without sacrificing your natural expressions, Restylane Refyne may be exactly what you've been looking for. Our team at Dermatology Experts is here to answer your questions, walk you through your options, and create a treatment plan that fits your face and your goals.
Call us today at (954) 726-2000 to schedule your consultation. Same-day appointments are available at our Miami, Parkland, and Tamarac locations. HSA and FSA funds may be used toward your treatment. We look forward to seeing you.







