Restylane Defyne
Soften deep lines and restore natural movement to your face with Restylane Defyne, available at three convenient South Florida locations.

Before and after gallery
Real results from honest, board-certified dermatology in South Florida
Your Face Should Move. Your Lines Don't Have To.
If you've noticed that the lines around your mouth and chin have deepened over time, you're not alone. South Florida's sun-drenched lifestyle is one of the things that makes living here wonderful, but years of UV exposure, outdoor activity, and natural aging can all contribute to more pronounced nasolabial folds and marionette lines. By your 40s or 50s, those creases can look etched in, even when your face is relaxed.
The good news is that you don't have to choose between looking frozen and looking your age. Restylane Defyne is a hyaluronic acid filler specifically designed to soften deep facial lines while preserving the natural movement and expressions that make you look like yourself. At Dermatology Experts, this treatment is performed under the direct care of Dr. Angelo Ayar, a board-certified dermatologist, not a medspa technician.
What Is Restylane Defyne?
Restylane Defyne is an FDA-approved injectable hyaluronic acid filler formulated with XpresHAn Technology, a cross-linking technology that allows the gel to flex and adapt naturally with your facial movements. Unlike older or stiffer fillers, Defyne is designed to move with you, so results look natural whether you're smiling, laughing, or speaking.
It is used primarily to treat moderate to severe deep facial lines, including nasolabial folds and marionette lines. It can also be used for chin augmentation and to restore volume in areas where the face has lost definition over time.
- FDA-approved for moderate to severe facial lines and wrinkles in adults
- Hyaluronic acid-based, a substance naturally found in the body
- XpresHAn Technology allows the filler to move with facial expressions rather than staying rigid
- Reversible with hyaluronidase if ever desired
- Results can last up to 12 months or longer for many patients
- Contains lidocaine to improve comfort during injection
- Performed in-office with no general anesthesia required
What to Expect at Your Appointment
At Dermatology Experts, every Restylane Defyne treatment begins with a thorough consultation. Dr. Ayar will assess your facial anatomy, discuss your goals, and map out a personalized treatment plan before a single injection is made. This is not a one-size-fits-all approach.
- Consultation: Dr. Ayar reviews your concerns, examines the treatment area, and confirms you are a good candidate
- Preparation: The skin is cleansed and a topical numbing agent may be applied for added comfort
- Injection: Restylane Defyne is carefully injected into targeted areas using a fine needle or cannula, depending on the treatment site
- Session length: Most appointments take 30 to 45 minutes from start to finish
- Downtime: Minimal. Most patients return to normal activities the same day
- Post-treatment: Mild swelling, redness, or bruising at injection sites is common and typically resolves within a few days
- Avoid: Strenuous exercise, alcohol, and excessive sun exposure for 24 to 48 hours after treatment
Because the formula contains lidocaine, discomfort during the procedure is generally mild. Many patients find the experience far more comfortable than they expected.
What Kind of Results Can You Expect?
Most patients notice visible improvement immediately after treatment, with final results becoming more apparent once any swelling has settled, typically within one to two weeks. Because Restylane Defyne is designed to integrate naturally with facial tissue, results tend to look smooth and proportional rather than overfilled.
- Visible softening of nasolabial folds and marionette lines
- Improved facial contour in the chin and lower face when treated in those areas
- Natural-looking results that allow full facial movement and expression
- Duration: Results may last up to 12 months or longer, depending on individual metabolism, lifestyle, and treatment area
- Touch-up treatments can help maintain results over time
It is important to have realistic expectations. Restylane Defyne can significantly improve the appearance of deep lines and restore a more rested, refreshed look, but individual results vary. During your consultation, Dr. Ayar will give you an honest assessment of what is achievable for your specific concerns.
Who Is a Good Candidate for Restylane Defyne?
Restylane Defyne may be a good fit for adults who want to address moderate to severe facial lines without surgery or significant downtime. If you recognize yourself in any of the following, this treatment may be worth discussing with Dr. Ayar:
- You have noticeable nasolabial folds or marionette lines that bother you at rest
- You want results that look natural, not frozen or overfilled
- You are in good overall health and have realistic expectations
- You are not currently pregnant or breastfeeding
- You do not have a known allergy to hyaluronic acid or lidocaine
- You want a non-surgical option with minimal recovery time
- You have lost facial volume in the lower face due to aging
- Previous filler treatments have left you wanting better movement and flexibility in your results
Patients with certain skin infections, bleeding disorders, or those taking blood-thinning medications may need to discuss timing and precautions with Dr. Ayar before proceeding. Your safety and comfort always come first.
Frequently Asked Questions About Restylane Defyne
How is Restylane Defyne different from other Restylane products?
The Restylane family includes several products formulated for different purposes and depths of correction. Defyne specifically uses XpresHAn Technology, which creates a more flexible gel structure that moves naturally with facial expressions. This makes it particularly well-suited for deeper lines in areas of the face that move a lot, such as around the mouth and chin. Other Restylane products may be better suited for fine lines, lip enhancement, or under-eye hollows. Dr. Ayar can help you determine which product, or combination of products, makes the most sense for your goals.
Does the injection hurt?
Most patients find Restylane Defyne injections very tolerable. The formula contains lidocaine, a local anesthetic, which helps reduce discomfort as the product is administered. A topical numbing cream can also be applied beforehand for added comfort. You may feel a mild pinching or pressure sensation during the injection, but significant pain is not typical. If at any point you are uncomfortable, let your provider know right away.
How long does Restylane Defyne last?
For many patients, results last up to 12 months or longer. Individual results vary depending on factors such as your metabolism, the area treated, and how much product was used. Areas with more movement, such as around the mouth, may metabolize filler more quickly than less mobile areas. Scheduling a touch-up appointment before results fully fade can help maintain a consistent look over time.
Is there anything I should avoid before or after my treatment?
Before your appointment, it is generally recommended to avoid blood-thinning medications and supplements such as aspirin, ibuprofen, fish oil, and vitamin E for about one week, as these can increase the chance of bruising. After treatment, avoid strenuous exercise, alcohol, and prolonged sun exposure for 24 to 48 hours. Applying a broad-spectrum sunscreen is always important in South Florida, and it is especially so in the days following any injectable treatment. Dr. Ayar's team will provide you with specific aftercare instructions tailored to your treatment.
Is Restylane Defyne covered by insurance?
Restylane Defyne is considered a cosmetic treatment and is not covered by health insurance. However, the cost may be eligible for payment using HSA or FSA funds, depending on your plan. We recommend confirming eligibility with your benefits provider before your appointment. During your consultation, Dr. Ayar's team can give you a clear cost estimate based on the amount of product needed to achieve your goals, so there are no surprises.
Why Choose Dermatology Experts for Restylane Defyne in South Florida?
There is no shortage of places offering injectable fillers in South Florida, from medspas to plastic surgery centers to pop-up injection events. What sets Dermatology Experts apart is the combination of genuine clinical expertise, a thoughtful approach to facial aesthetics, and the kind of patient care that has earned the practice more than 500 five-star reviews.
- Led by Dr. Angelo Ayar, MD, FAAD, a double board-certified dermatologist trained at the University of Michigan, one of the most respected dermatology programs in the country
- Deep expertise in skin health and facial anatomy from a physician who understands how aging, sun exposure, and skin quality all interact, not just how to place filler
- Full-spectrum dermatology care under one roof, including medical, surgical, and cosmetic services
- Three convenient South Florida locations in Miami, Parkland, and Tamarac, serving Broward County, Miami-Dade County, Coral Springs, Fort Lauderdale, Pompano Beach, and Boca Raton
- Same-day appointments available so you don't have to wait weeks to be seen
- A team consistently described by patients as warm, attentive, and genuinely caring
When you come to Dermatology Experts for Restylane Defyne, you are not checking in at a factory. Dr. Ayar takes the time to understand your face, your goals, and what a natural result actually means to you. That approach makes all the difference.
Ready to Soften Those Lines? Let's Talk.
If you've been thinking about addressing deeper facial lines and want results that look like you, only refreshed, Restylane Defyne may be exactly what you've been looking for. Dr. Ayar and the team at Dermatology Experts are ready to answer your questions and help you decide if this treatment is the right fit.
Call us today at (954) 726-2000 to schedule your consultation. Same-day appointments are often available. HSA and FSA funds may be used toward the cost of treatment. With three locations across South Florida in Miami, Parkland, and Tamarac, expert dermatology care is never far away.







